A drug-free pill for sustained appetite suppression.
Meet Sirona — a once daily hydrogel pill that gently expands in the stomach to create a sustained feeling of fullness, helping reduce calorie intake without medication.
How Sirona works, step by step
A simple daily routine — no drugs, no surgery, no injections.
Taken once daily
Sirona is taken once daily as a convenient oral pill — part of your normal routine.
Sustained satiety
Once in the stomach, Sirona expands to reduce available volume and stays for several days — providing sustained appetite suppression that reduces calorie intake.
Passes naturally
Sirona then breaks into smaller pieces that are excreted naturally, just like food.
Proven across two clinical trials
Sirona's effect on appetite and weight has been studied in two UK clinical trials, with more than 9,500 pills dosed. The headline results are now published in the peer-reviewed journal Obesity.
Change in mean daily calorie intake
Change from baseline at 24 weeks · kcalBars show mean change from baseline; whiskers indicate variability. Participants on Sirona consumed ~400 fewer calories per day than those on placebo.
Total body weight loss over time
Mean % change from baselineIndividuals with Class 1 obesity on Sirona reached −6.4% total body weight loss at 24 weeks; placebo reached −1.0% at 12 weeks. Whiskers indicate variability.
Three target markets Sirona was designed for
Individuals living with overweight
Many people in this range aren't eligible for GLP-1 therapies like Wegovy and Mounjaro, and don't need their intensity. Sirona is an early intervention to help return to a healthy weight and prevent progression into obesity.
An alternative to anti-obesity medications
A treatment option for people who cannot, or simply prefer not to, use pharmacotherapy for their weight loss — without injections or systemic drugs.
Support post anti-obesity medication
Sirona is uniquely positioned to support people transitioning off anti-obesity medications (e.g. GLP-1s), helping to minimise weight regain and maintain their new weight long term.
But don't just take our word for it
Real experiences from participants across our UK clinical trials.
”I have lost weight & feel like I have control over what I eat.
UK clinical trial participant
”Great weight loss without [the] psychological battle with my brain and body.
UK clinical trial participant
”I felt less hungry… I had to make an effort to eat.
UK clinical trial participant
Built to medical-device standards
Sirona has completed its second UK clinical trial and is pending regulatory approval in Europe. It is manufactured in OMP's own ISO 13485 and ISO 9001 certified facility.
Interested in Sirona?
For partnership, clinical or media enquiries, our team would love to hear from you.
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